Daily Archives: February 10, 2017

INFLAMMATION: THE IMPLICATION WITH WEIGHT GAIN

INFLAMMATION: THE IMPLICATION WITH WEIGHT GAIN

The connection between inflammation and diet is clear. Low-grade inflammation disrupts weight-control mechanism. When people gain weight, the extra fatty tissues produces leptin, a hormone that suppresses appetite and speeds metabolism. In theory, this should cause people to lose the extra weight. Instead, inflammation in fat tissue and blood vessels stimulates the production of anti-inflammatory chemicals. Theses chemicals disable leptin’s ability to suppress appetite and speed metabolism. This is called leptin resistance.
To combat leptin resistance, I have developed a fat-resistance diet based on cutting edge research done at major universities and teaching hospitals. Eating the proper foods can eliminate chronic inflammation and reprogram the body’s weight-loss mechanism. Only real foods provide key anti-inflammatory nutrients. Artificial sweeteners and fat substitutes do not have such nutrients.
1 ) Eat fish 3 times a week. The omega-3 fatty acids in fish have powerful anti-inflammatory properties. Fish rich in omega-3s are: anchovies, conch, herring,
mackerel, sablefish, salmon, sardines, sturgeon, and tuna. Also, flaxseed, walnuts, beans.
2) Balance essential fatty acids. The optimal ratio of omega-6 to omega-3 fatty acids is 1:1. The ratio in the average American diet is 20:1. An excess of omega-6 fats in tissue leads cells to produce excessive levels of pro-inflammatory chemicals called prostanoids. Foods high in omega-6s: red meat, chicken, milk, eggs, and most vegetable oils.
3) Cut back on saturated fat – found primarily in beef, pork, lamb, dairy products, and poultry skin – to no more than 10% of total calories … Unless free ranging, grass feed, organic meat. These meats conform to the 10% fat rule. Do not eat any trans fat – any foods made with hydrogenated or partially hydrogenated vegetable oil.
4) Get 25 grams of fiber a day. A diet high in fiber helps control appetite and reduce inflammation. People who consume the most fiber have lower levels of C-reactive protein (CRP), which indicates the presence of inflammatory chemicals in the body.
5) Eat colorful fruits and vegetables. Aim for 9 servings a day. Deeper colors and intense flavors indicate foods high in flavonoids and carotenoids, chemical compounds that have anti-inflammatory effects. Anthocyanins, among the most potent anti-inflammatory agents are found in blueberries, cherries, or pomegranates.
6) Choose alliums and crucifers. Crucifers include broccoli, cauliflower, cabbage and kale. Alliums include onions, and garlic.

GAINING WEIGHT: MEDICATION MAY BE THE PROBLEM

GAINING WEIGHT: MEDICATION MAY BE THE PROBLEM

Don’t look just to your diet. Look in your medicine cabinet. It’s not unusual for patients to gain at least five pounds after they start on certain medications. Here are just a few:
1 ) Many serotonin selective reuptake inhibitors (SSRIs) cause an average weight gain of 7%. Some SSRIs such as Paxil are more likely to cause weight gain than others.
These drugs increase levels of serotonin, a neurotransmitter that is involved in appetite and satiety. People who take them may feel hungrier in general and not feel full after eating. Other, chemically similar, drugs such as Zoloft, Welbutrin, or Effexor are less likely to cause weight gain.
2) Antipsychotics. 60% of patients taking the new anti-psychotics gain significant amounts of weight in the firs year. Those taking Zyprexa may gain more than 30 pounds. Those taking Clozaril average an 11-pound weight gain.
3) Hormones. The hormones used in birth control pills and to relieve menopausal discomfort (HRT) appear to cause weight gain in about 25% of patients. The contraceptive injection, Depo-Provera, causes weight gain in up to 70% of users. Non-hormonal methods and Ortho Tri-cyclen, mimic the body’s cycle, which may minimize weight gain.
4) Evista. Helps prevent osteoporosis but a small percentage of women who take it gain weight. Try Fosamax instead.
5) Neurontin. For seizures appears to cause alterations in carbohydrate metabolism and effect parts of the brain that control appetite. 10% of patients who take it gain weight. The drug Dilantin doesn’t cause weight gain.
6) Steroids. Increase appetite and cause weight gain.
7) Tamoxifen. Used to prevent cancer reoccurrence in women who have undergone surgery or other treatments for breast cancer. Some studies show that women who take tamoxifen may gain up to 25 pounds over three years.

ANTIBIOTICS AND YOUR WAISTLINE

Antibiotics kill germs and bad bacteria, but they also kill good bacteria. And here’s what happens when we expose ourselves to antibiotics from many different sources in our society: from penicillin to flu shots to the antibiotics given to farm animals. Bacteria and other intestinal microbes adjust the level of the hormones ghrelin and leptin, which regulate appetite and metabolism. Certain microbes seem to be associated with a desire for chocolate according to research by the Nestle Research Center. A recent study suggests that emotional stress triggers an explosion in the population of B. theta, the starch-digesting bacteria associated with weight gain.
From birth, microbes colonize us. After birth, while our immune system is still undeveloped these microbes learn to tolerate or destroy foreign substances. The immune cells in the respiratory and digestive systems sample all the microbes we inhale or swallow. When they see the same ones over and over (fats and sugars), they then secrete an anti-inflammatorily substance that signals the microbe-killing T-cells to stand down.
In order for the immune system to know which bacteria are good or bad, they sample all the microbes we inhale or swallow. The essentials steps in the development of a healthy immune system begin at birth. But there is a fine line between recognizing substitutes as foreign and deadly, or harmless. But to develop a properly functioning immune system, it must be exposed to a wide range of harmless microbes early in life. This was the normal condition of most human infants until just a few generations ago.
Now, from the day we are born we are exposed to antibiotics in the food we eat or in the form of preventative injections, and kept in a sterile, perfectly clear environment. Cover the dirt floor, banish farm animals to a distant feed lot, treat the ear infection with penicillin and the inflammation-calming lnterleukin-10 reaction may fail to develop properly. And inflammation is now considered the greatest risk factor for heart disease and stroke.
Modem sanitation, to an extent, is a good thing, but keeping the children at a safe distance from all microbes and it tips the immune system in the direction of over reaction, whether to outside stimuli or even to the body’s own cells. If the immune system is not familiar with external micros, it launches an extreme (what would be a minimal assault if faced earlier in life by an as yet undeveloped immune system) assault resulting in allergies and asthma. But if the immune system turns on the body itself, then you see irritable bowel syndrome, lupus, or MS among many other autoimmune diseases that were virtually unknown to our ancestors., but are increasingly common in the developed world.
The answer is to minimize immunization and expose young children to a wide range of harmless germs like those found in a playground or a park. And treat all saturated fats and sugars are foreign substances, because, very quickly, right after birth, the body learns to disregard them.
One microb in particular, Mycobacterium vaccae, is found I the soil in East Africa. That has a powerful effect on the immune system. It was tested by the university of Bristol as a cancer therapy. The results showed, indeed, that it had anti-cancer properties. But what was just as impressive was that cancer patients felt better regardless of whether or not their cancer was actually improving. When scientists injected mice with Mycobacterium vaccae, they found it activated the serotonin receptors working like an anti-depressant.